While folic acid was, at one time, considered protective against cancers, it's now said it may actually promote certain ones. First, a study of 643 men at University of North Carolina at Chapel Hill School of Medicine found that high doses of folic acid supplements failed to prevent colon cancer. Then another analysis of the same study's finding suggests a link between folic acid supplements an increased risk for prostate cancer. In the study, the men who took high doses of the vitamin saw a 163 percent risk increase in prostate cancer compared to men who did not take folic acid supplements. Some researchers conclude that folate is unlikely to be beneficial in regard to certain cancers—and may actually be harmful. More research is needed.
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